ChemicalBook >> CAS DataBase List >>Dicyandiamide


Chemical Name:
CYANOGUANIDINE;DICYANODIAMIDE;DCD;N-Cyanoguanidine;1-CYANOGUANIDINE;2-Cyanoguanidine;Metformin impurity A;DICY;Dermcidin;Guanidine-1-carbonitrile
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:

Dicyandiamide Properties

Melting point 208-211 °C (lit.)
Boiling point 144.35°C (rough estimate)
Density 1.40
refractive index 1.6260 (estimate)
storage temp. 2-8°C
solubility H2O: 0.1 g/mL, clear
pka 0.73±0.70(Predicted)
form Crystalline Powder
color White
Water Solubility 32 g/L (20 ºC)
Merck 14,3092
BRN 605637
Stability Stable. Incompatible with strong acids, strong oxidizing agents, strong bases.
CAS DataBase Reference 461-58-5(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances CYANOGUANIDINE
FDA 21 CFR 175.105; 175.300; 176.170; 177.2470; 177.2600; 178.2010
EWG's Food Scores 1
NIST Chemistry Reference Dicyandiamide(461-58-5)
EPA Substance Registry System Dicyanodiamide (461-58-5)


Risk and Safety Statements

Hazard Codes  Xn,T
Risk Statements  20/21/22-43-36/38-25
Safety Statements  22-24/25-45-36-3
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  1
RTECS  ME9950000
HS Code  29262000
Toxicity LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg

Dicyandiamide price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB1306514 ANTI-DCD(C-TERMINAL) antibody produced in rabbit purified immunoglobulin, buffered aqueous solution 461-58-5 400μl $427 2022-05-15 Buy
Sigma-Aldrich D76609 Dicyandiamide 99% 461-58-5 1kg $53 2022-05-15 Buy
Sigma-Aldrich 8.02491 1-Cyanoguanidine for synthesis 461-58-5 100g $25.9 2022-05-15 Buy
Sigma-Aldrich 8.02491 1-Cyanoguanidine for synthesis 461-58-5 1kg $48.7 2022-05-15 Buy
Sigma-Aldrich 1396310 Metformin Related Compound A United States Pharmacopeia (USP) Reference Standard 461-58-5 30mg $1270 2022-05-15 Buy
Product number Packaging Price Buy
SAB1306514 400μl $427 Buy
D76609 1kg $53 Buy
8.02491 100g $25.9 Buy
8.02491 1kg $48.7 Buy
1396310 30mg $1270 Buy

Dicyandiamide Chemical Properties,Uses,Production

Chemical Properties

white powder


Dicyandiamide is a guanidine derivative used in the synthesis of barbiturates,it is also used in the plastics industry (manufacture of melamine).


In the plastics industry (manufacture of melamine). In the pharmaceutical industry (barbiturates, guanidine derivatives).


Dicyandiamide is used in the synthesis of barbiturates. It is used as a stabilizer of ammonium dinitramide melt. It is used as hardener.


Dicyanodiammonia, abbreviated as dicy or DCD. It is an organic substance with the chemical formula of c2h4n4. It is a dimer of cyanamide and a cyano derivative of guanidine. Chemical formula c2h4n4. White crystalline powder. Soluble in water, alcohol, ethylene glycol and dimethylformamide, almost insoluble in ether and benzene. Stable when dry. It is a guanidine in which one of the amino hydrogens of guanidine itself is substituted by a cyano group. It is used in the manufacture of fertilizers, pharmaceuticals, explosives, oil well drilling muds, and dyestuffs. It has a role as a curing agent, a flame retardant, a fertilizer, an explosive and a nitrification inhibitor. It is a member of guanidines and a nitrile. The application of nitrification inhibitors has been used as a strategy to promote N utilization efficacy and reduce N2O emissions in paddy Dicyandiamide (DCD) as a widely used nitrification inhibitor inhibits the activity of ammonium-oxidizing bacteria which results in longer ammonium retention and reduces the production of NO2?in soils. DCD efficacy was found to be related to DCD concentration, temperature, moisture, pH, and organic matter content. Studies have shown that leaching DCD from agricultural soils into aquatic ecosystems can strongly change the community composition of benthic stream bacteria and algae and influence stream nutrient cycling stoichiometry. Literature on the mechanisms and benefits of nitrification inhibitors is extensive but there are very few studies focused on the influence of DCD application on other microbes in paddy system.

Production Methods

Dicyanodiamide is manufactured by dimerization of cyanamide in aqueous solution. The 25% cyanamide solution produced is adjusted to pH 8–9 and held at approximately 80C for 2 h to give complete conversion. The hot liquor is filtered and transferred to a vacuum crystallizer, where it is cooled. The crystals or dicyanodiamide are separated in continuous centrifuges and passed to rotary driers. In 1990, the total worldwide production of dicyanodiamide was about 30,000 tons.

General Description

Dicyandiamide is commonly used for the curing of epoxy resins. It is a nitrification inhibitor that is said to be capable of reducing nitrate (NO3-) leaching and nitrous oxide (N2O) emissions from grazed pasture soils.

Chemical Synthesis

The calcium hydrogen cyanide suspension obtained from the hydrolysis of calcium cyanamide is filtered under reduced pressure to remove the calcium hydroxide filter residue, and then carbon dioxide is introduced into the filtrate to precipitate the calcium in the form of calcium carbonate to obtain the cyanamide solution. It is polymerized under alkaline conditions, then filtered, cooled, crystallized, separated and dried to obtain dimer cyanamide. The temperature at the maximum rate of dicyandiamide formation is related to pH: pH is 9.7 at 50 ℃; PH 9.1 at 80 ℃; The pH is 8.8 at 100 ℃. After controlled polymerization under these conditions, the finished dicyandiamide is obtained by cooling, crystallization, separation and drying. The content of dicyandiamide in industrial products is 99%, and 4239kg of lime nitrogen (more than 21% nitrogen) is consumed per ton of products.

Purification Methods

Recrystallise cyanoguanidine from water or EtOH. [Beilstein 3 IV 160.]

Global( 702)Suppliers
Supplier Tel Email Country ProdList Advantage
Ningxia Jinhua Chemical Co.,Ltd
025-52279164 China 68 58
+86-852-30606658 China 24790 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 China 19994 60
Hangzhou Bayee Chemical Co., Ltd.
0086-571-86990109 China 105 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 China 22021 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 China 1809 55
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418679 China 2995 55
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967 China 1011 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3623 58
career henan chemical co
+86-0371-86658258 China 29960 58

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  • Jan 19,2022

View Lastest Price from Dicyandiamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2022-03-17 Dicyandiamide
US $12.00 / kg 1kg 99% 30 tons XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
2022-03-04 Dicyandiamide
US $100.00 / bag 1bag 99 500 Shanxi Naipu Import and Export Co.,Ltd
2022-02-25 Dicyanodiamide
US $0.00 / Kg/Bag 1KG 99.5% 2000mt Jinan Finer Chemical Co., Ltd
  • Dicyandiamide
  • US $12.00 / kg
  • 99%
  • Dicyandiamide
  • US $100.00 / bag
  • 99
  • Shanxi Naipu Import and Export Co.,Ltd
  • Dicyanodiamide
  • US $0.00 / Kg/Bag
  • 99.5%
  • Jinan Finer Chemical Co., Ltd
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